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The American Diabetes Association (ADA) recommends insulin as the preferred agent for glycemic control during pregnancy due to its established safety profile and inability to cross the placental barrier in significant amounts
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Variants in the GLP1R gene (such as rs6923761) affect receptor expression and sensitivity, potentially determining whether your stomach responds to GLP-1 with significant slowing or minimal change
Diabetes (2012) 61(11):296779
Another observational study from 2024, titled Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide, noted an association between semaglutide, the main drug in Ozempic, and Non - Arteritic Ischemic Optic Neuropathy (NAION), an ocular disease which can cause permanent and severe vision loss
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