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[3] immune modulatory responses, which involve the reduction of pro-inflammatory cytokine and nitric oxide (NO) production, as well as the promotion of immunosuppressive macrophage (M2) formation [123, 124]

Excess supplementation may alter detoxification pathways or electrolyte balance, potentially worsening organ stress if not medically supervised

Nat Med 28:911923 Correia AS, Vale N (2022) Tryptophan metabolism in depression: a narrative review with a focus on serotonin and kynurenine pathways

ALOX15-launched PUFA-phospholipids peroxidation increases the susceptibility of ferroptosis in ischemia-induced myocardial damage

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J Am Acad Dermatol 67(4):630635 Kardaun SH, Sekula P, Valeyrie-Allanore L, Liss Y, Chu CY, Creamer D, Sidoroff A, Naldi L, Mockenhaupt M, Roujeau JC et al (2013) Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction