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The results suggest that defatting did not have a negative effect on the isoelectric pH precipitation method with respect to the separation of proteins from non-protein components
Furthermore, both r-sFNDC5 and r-irisin significantly improved glucose tolerance in obese mice as demonstrated in the glucose tolerance test (GTT) and significantly reduced levels of fasting insulin in the insulin tolerance test (ITT) (Figure 6C)
The developing company then sends the test evidence to CDER
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