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Dihexa activates the HGF/c-Met pathway, stimulating synaptogenesis (the creation of new connections between neurons)

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Comparison with structures of the AMY 1 R bound to non-lipidated peptides (CagriBB and rAmy) revealed that the lipid conjugation does not affect the conformation of the peptide, nor the receptor when Cagri is stably engaged

3), and the backbone of each complex also closely resembled the previously determined active structures of individual AMYRs bound to rat Amy (rAmy) 15 (Fig

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