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There is no official dose since it is not approved - start conservative and increase gradually

A substance can sit on the 503A list without ever having completed the clinical trial programme an approved drug requires

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Some providers specifically prefer B12-containing formulations because their patients on calorie-restricted diets may develop nutritional gaps that B12 supplementation helps address

Messing, J., Thle, C., Niehues, M., et al

Additionally, vitamin B12 deficiency can cause paresthesia or numbness in the limbs