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Humoral immunity involves autoreactive B cells and plasma cells that produce high-affinity antibodies against Tg and TPO, furthering tissue injury through complement activation and antibody-dependent cell-mediated cytotoxicity (ADCC)

The body responds with localized inflammation

Collagen fibers aligned more appropriately along lines of stress, suggesting functional tissue rather than disorganized scar tissue

Mechanisms of pulmonary fibrosis

Its systemic nature allows it to reach the gastrointestinal tract and exert its protective and healing properties.

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