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We employed a Boolean search strategy using the terms tirzepatide OR LY3437943, applying these terms exclusively to the titles of documents
In one large clinical trial, skin reactions were reported in approximately 5-10% of participants
Semaglutide was the most cost-effective treatment compared to exenatide, dulaglutide, liraglutide, or no treatment in short-term analyses (approximately one and a half years) that assessed quality-adjusted life years and incremental cost-effectiveness ratios [135,136,137,138,139,140,141,142,143,144]
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Patients who have associated high-risk conditionssuch as cardiovascular disease, prediabetes, or a substantial genetic predisposition to metabolic disordersmay particularly benefit from the comprehensive metabolic improvements offered by Retatrutide if they have failed other therapies
