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Slowing dose escalation is the standard approach, since gastrointestinal effects usually ease as the body adjusts over several weeks
A higher weekly dose of semaglutide helped adults with obesity lose about 19 percent of their body weight, and it did so over a long, carefully monitored period that followed strict protocols and consistent follow up visits
What to Expect Individual responses vary
Specific lifestyle changes can help individuals stay healthy and keep the weight off: Dose Tapering While patients can stop taking GLP-1s without serious side effects, it is critical to wean off the medication rather than stop taking it suddenly
Exp Mol Med 48:e219e219
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