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By integrating human clinical studies, postmortem analyses, and preclinical mouse models, this study establishes a mechanism in which astrocytic GABA dysregulation disrupts prefrontal circuits, impairs fear extinction, and modulates CBF
No representations are made regarding biological activity, physiological outcomes, or experimental effects
As a result of alteration of permeability, the cell membrane is unable to function as a selective barrier, and potassium and other cellular constituents are lost
Primary outcomes The primary outcomes are as follows: fatal and non-fatal CVD events, including coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation (AF)
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