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However, the clinical utility of native GLP-1 is limited due to its extremely short half-life (only a few minutes), as it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)

Study design The Phase 2 trial was a randomized, double-blind, placebo-controlled study that enrolled 338 adults with obesity (BMI 30 or higher) or overweight (BMI 27 or higher) with at least one weight-related condition

The lyophilized powder is reconstituted with bacteriostatic water, typically at a concentration of 500 micrograms per milliliter, which yields a convenient dosing volume of 0.5 mL for a 250-microgram dose

Heres a breakdown of the most commonly used medications: Exenatide (Byetta, Bydureon) Indication : Type 2 diabetes

Experts also suggest stopping other meds such as adapalene while you are pregnant