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Studies have shown that the MLH1 protein, critical for regulating the MMR pathway, when under-expressed owing to hypermethylation of the hMLH1 gene promoter, resulted in decreased sensitivity in cancer cells

Kolterman OG, Kim DD, Shen L, et al

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Enhanced labile plasma iron and outcome in acute myeloid leukaemia and myelodysplastic syndrome after allogeneic haemopoietic cell transplantation (ALLIVE): a prospective, multicentre, observational trial

Iron, magnesium, selenium, and B-complex vitamins support enzymatic velocity and mitochondrial metabolic throughput [100]