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These drugs do affect energy systems in the brain
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Finally, another report proposed the synthesis of PLGA nanocarriers decorated with PEG and glutathione (GSH), for the intracellular delivery of curcumin: the double functionalization resulted in an increased NP uptake by neuronal cells and, in particular, the GSH conjugation modified the NP internalization pathway, avoiding the lysosomal degradation and increasing the therapeutic fate for potential application in the treatment of AD (Paka and Ramassamy, 2017)
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L-trimethyl-3-hydroxy-ammoniabutanoate (l-Carnitine), a quaternary ammonium compound, is synthesized from methionine and lysine in cells 7
However, if symptoms are particularly troublesome, healthcare professionals may consider short-term symptomatic relief whilst the body adjusts to the medication
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