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A 2022 paper in the American Journal of Clinical Nutrition demonstrated that a proprietary extract of New Zealand bitter hops

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As an indirect antioxidant, SFN activates the Nrf2/Kelch-like ECH-associated protein 1 (Keap1)/Antioxidant response element (ARE) signaling pathway

By co-delivering chemotherapeutic agents that induce ICD with immunomodulators that reprogram the TME, these platforms can achieve synergistic antitumor effects that are not attainable with either modality alone (43, 61)

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However, this doesnt mean the papers hypothesis is right or that the data are close to the point of founding biotechs and starting clinical trials on people