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The cell type or animal model, test concentrations, exposure time, sampling schedule, and assay method should be stated clearly

Trends in Endocrinology & Metabolism, 31 (6), 410-421

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Recent data suggest potential benefits in heart failure with preserved ejection fraction (HFpEF) with obesity, but monitoring is important, particularly during initiation

Additional mice (n = 3/group) were administered with MEDI4166 at 10 mg/kg or Ab#2.1_EX4 at 10 or 30 mg/kg to determine human Fc and GLP-1R active compound concentrations by taking blood samples at the following times post-dosing: 2 h, 4 h, 8 h, 1, 3, 7, 14 and 21 days