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47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF
Eligibility is determined by a licensed healthcare provider based on individual goals, health history, and overall suitability
Though a daily pill requires more obedience than a weekly shot, it has a few advantages
It has potent anti-inflammatory effects , particularly in the gut, by inhibiting the production of pro-inflammatory cytokines
Acknowledgements The authors apologize for incomplete citations owing to rapid advancement of the field
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