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The compound reduces hypertension, hyperlipidemia, and other cardiovascular risk factors that commonly accompany insulin resistance and metabolic syndrome
It discloses that compounded medications are not FDA-approved
Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells
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