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Taste changes may relate to delayed gastric emptying, GLP-1 receptor activity in taste buds and brain reward centres, or accompanying gastrointestinal symptoms like nausea

Progress Monitoring Progress should be measured by more than scale weight

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The drug has a long half-life, which means it can be administered monthly or less frequently, giving the drug the potential to improve adherence and long-term weight control, according to Jay Bradner, executive vice president of research and development at Amgen

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They have been used for years to help manage type 2 diabetes