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Anabolic Signaling in Preclinical Models In preclinical models, activation of this pathway is associated with several downstream signaling events: increased protein synthesis via mTOR activation, stimulation of satellite cells that contribute to muscle fiber development, and inhibition of the FOXO pathway, which under normal conditions promotes protein breakdown

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References Raun, K., Hansen, B.S., Johansen, N.L., Thgersen, H., Madsen, K., Ankersen, M., & Andersen, P.H

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Precision microbiome modulation with discrete dietary fiber structures directs short-chain fatty acid production