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The signaling mechanism may be facilitated by its anti-inflammatory properties through its effects on cell migration and cell division

Effect of naltrexone pretreatment on ketamine-induced glutamatergic activity and symptoms of depression: a randomized crossover study

Considering this, the elevated concentrations of these metabolites (sedoheptulose, mannoheptulose and 1.3-diaminopropane) are likely due to reduced growth and nucleotide synthesis due to nutrient deprivation, and a redirection of this pathway towards energy generation and preventing oxidative stress