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doi: 10.3390/MOLECULES25010189 96 AgusfinaMSaputriFCSaktiASMunimA
Goodwin PJ, Ennis M, Pritchard KI, Trudeau ME, Koo J, Madarnas Y, et al
The synthesis of orforglipron involves the assembly of three principal building blocks (the tetrahydropyran, indazole, and phenyl fragments) through sequential coupling reactions, followed by purification using standard crystallization and recrystallization techniques rather than expensive chromatographic methods
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