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The first category, growth-hormone secretagogues such as CJC-1295 and Ipamorelin, is proposed to stimulate the pituitary gland's own growth-hormone release and downstream IGF-1 output, an approach tied to lean mass and recovery support in the research reviewed for this list

Multiple Cellular Pathways in Skin Repair Laboratory studies report effects on collagen synthesis, glycosaminoglycan production, MMP-2 expression, TIMP-1 and TIMP-2, and extracellular matrix remodeling in fibroblast or wound-related models [4], [5], [12]

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