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However, the human evidence remains heterogeneous, and mixed findings may occur depending on study design, outcome definitions, and duration of exposure

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Mouse pancreas image quantification and analysis were performed on all islets in a single longitudinal cross-section of the pancreas cut at 5 M through approximately 1000 M of the whole pancreas tissue depth, as previously validated (111, 112) (1 cross-section per mouse, per antibody combination