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February 16, 2025 10:00 View More GLP-1 Agonists: The Medical Revolution Beyond Weight Loss In this podcast episode, McCall McPherson, a medical professional from the Modern Thyroid Clinic, explores the benefits of GLP-1 agonists, originally developed for diabetes

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GLP-1 receptor activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying in research models GIP receptor activation potentiates insulin secretion and modulates adipose tissue metabolism in preclinical studies Glucagon receptor partial agonism supports hepatic glucose output modulation and increased energy expenditure at physiological concentrations in research models The simultaneous engagement of all three receptors produces coordinated effects on insulin secretion, glucagon suppression, energy expenditure, and metabolic signaling studied in preclinical models and referenced in peer-reviewed literature

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