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Direct NAD+ IV Tolerability A small 2026 commercial-infusion study reported short-term tolerability data and variable exploratory metabolic outcomes, with more research needed beyond 30 days

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As highlighted in a recent review, while GLP-1RAs show potential in treating SLE, further prospective investigations are needed to determine if they pose a risk of triggering autoimmune activity and whether their advantages in SLE outweigh such risks [292]