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SEPS1 contributes to the removal and transfer (retrotranslocation) of misfolded proteins from the ER lumen to the cytosol where proteins are tagged with ubiquitin before being degraded

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However, naloxone, an opioid antagonist, has no effect ( Neuropeptide Y Neuropeptide Y (NPY) is found mainly in the CNS and sympathetic nerves (Ekblad et al., 1984)

doi:10.1042/bj0302085

A method of increasing ATP and/or glutathione