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Fatigue can happen because of many reasons, from nutrient deficiencies and insufficient sleep to serious conditions like anemia and thyroid issues

Her imaging demonstrated return of lymphatic pumping and she experienced a significant improvement in quality of life, assessed by a validated lymphedema-specific patient reported outcome (PROM)

These steps ensure compliance and protect patients

J Biol Chem (2009) 284:2432840

Regular follow-up schedule during maintenance therapy typically includes: Clinical visits every 3-6 months to assess weight trends, side effects, and comorbidity status Laboratory monitoring as clinically indicated (lipid panel, hemoglobin A1c if diabetic, liver function tests if indicated) Blood pressure monitoring given expected improvements with weight loss Nutritional assessment to ensure adequate protein and micronutrient intake during weight loss Patients should be empowered to contact their healthcare provider between scheduled visits if concerning symptoms develop, including persistent gastrointestinal symptoms, signs of gallbladder disease, severe abdominal pain, or symptoms of hypoglycemia

There has been a marked increase in the use of these medications since they were first approved for weight loss in 2014, particularly following the approval of Wegovy in 2021 and Zepbound in 2022