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It means physician supervision, appropriate patient selection, and honest conversations about what the evidence does and doesn't support

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Never discontinue B12 injections without medical advice, even if you feel completely well, as deficiency can recur and cause irreversible neurological damage if left untreated

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A mismatch can develop between the haptocorrin-bound pool, which makes up most of the total, and the smaller active fraction on transcobalamin that cells depend on

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