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Most providers recommend waiting 4872 hours after injection to allow injection-site healing and metabolic stabilization
The half-life of retatrutide is estimated at approximately six days based on phase 1 pharmacokinetic data, broadly similar to tirzepatide [2]
This means your doses will be gradually increased so that your body can adjust to the medication and you can manage potential side effects
PMID 30288368
[A] Jens Juul Holst: What I have provided is physiology and I have provided it to the pharmaceutical industry
Retatrutide Titration Retatrutide Titration Schedule: Phase 2 Standard and Slow Protocol The retatrutide titration schedule from the Phase 2 trial escalates from 2mg to 4mg to 8mg to 12mg, every 4 weeks (Jastreboff et al., NEJM 2023)
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