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Research shows treated animals lost an average 5.1% body weight, 30% reduction in adipocyte size and 35% decrease in white adipose tissue mass
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More serious but rare adverse events include pancreatitis, gallbladder events, and hypoglycemia (primarily in patients using insulin simultaneously)
This effect is consistent with what has been observed with other GLP-1 based compounds and is thought to reflect a combination of weight-mediated reduction in vascular resistance and direct vascular effects of GLP-1 receptor activation
When researchers study how this enzyme behaves, they can observe how cellular energy pathways respond
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