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Clin Gastroenterol Hepatol 18(1):5768

The time point was selected at 9:00 prior to NTG injection

Its unique role in the brain-gut axis supports both gut health and neuroprotection, influencing neurotransmitter balance and nerve regeneration, making it relevant for inflammatory disorders, injuries, and neurodegenerative diseases

Adolescents undergo immunological changes, including functional changes in glial cells and the BBB, although it is not clear whether these changes are tied to those in the gut microbiota [37]

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19 Particularly compelling is the observation that pharmacological inhibition of vesicle biogenesis with GW4869 restricts the spatial expansion of tubular injury, supporting a causal role for extracellular vesicle-mediated propagation in vivo