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Agents targeting the apoptotic machinery, such as Bcl-2 and Bcl-xL inhibitors, counteract anti-apoptotic signaling and promote tumor cell apoptosis [278]
We reveal connections between -lactam susceptibility, peptidoglycan synthesis, and blockages in undecaprenyl phosphate metabolism
Chaiklahan R, Chirasuwan N, Loha V, Tia S, Bunnag B (2018) Stepwise extraction of high-value chemicals from Arthrospira (Spirulina) and an economic feasibility study
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In vitro and animal studies have found that lipoic acid exhibits immunomodulatory properties through mechanisms that stimulate the production of cyclic AMP (cAMP) (90, 91) a central regulator of innate immune functions and inhibits the migration of immune cells into the brain and spinal cord (92), possibly by decreasing endothelial expression of cell adhesion molecules, inhibiting expression of enzymes like matrix metalloproteinases (MMP), and/or reducing the permeability of the blood-brain barrier (87, 89, 93, 94)
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