Tirzepatide is a dual-agonist targeting GLP-1 and GIP receptors, while retatrutide is a triple-agonist that also activates the glucagon receptor
If you have a diagnosed metabolic condition, are on medication, or have specific dietary restrictions, it's worth speaking to your GP or a dietitian before making significant changes
Store unopened pens in the refrigerator until you are ready to start each one
Other common GI effects include vomiting, diarrhea, abdominal pain, and constipation , with varying frequencies across different semaglutide products
Compounded formulations use different excipients than brand-name products, which means the local tissue reaction profile may be different
Nat Rev Rheumatol (2009) 5(10):5727