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A randomized controlled trial published in the European Journal of Nutrition found that daily consumption of oral glutathione at 1,000 mg increased blood glutathione levels by 30-35% in red blood cells, plasma, and lymphocytes after 6 months of supplementation

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[127] studied MT-2A expression in visceral adipose and subcutaneous tissues of people with obesity with and without diabetes, and they showed that MT-2A might be involved in the modulation of insulin resistance in fat cells

The mean change in body weight from baseline to week 104 was -15.2% in the semaglutide group versus -2.6% with placebo

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