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Optineurin inhibits NLRP3 inflammasome activation by enhancing mitophagy of renal tubular cells in diabetic nephropathy

10 Conclusion and perspectives DKD, a serious DM-related microvascular disorder, is pathologically defined by persistent hyperglycemia-triggered complex metabolic abnormalities, ultimately leading to glomerular filtration barrier destruction and tubulointerstitial injury (13, 132, 224)

Insufficient qi in the high altitude condition results in insufficient zong qi, creating qi deficiency

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Factors such as diet, age, sex, and metabolic status have not been fully controlled

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