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The mechanism of AOD 9604 in subcutaneous adipose tissue Activation of fat breakdown (lipolysis) AOD 9604 promotes fat breakdown through the following pathways: Activation of the 3-AR signaling pathway: AOD 9604 binds to 3-AR on the adipocyte membrane, activates adenylic acid cyclase (AC), increases the intracellular cyclic adenosine monophosphate (cAMP) level, and thereby activates protein kinase A (PKA)
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Preclinical toxicology studies in rats and dogs at doses up to 20 times the projected human therapeutic dose showed no organ toxicity, no changes in IGF-1 levels, and no alterations in glucose homeostasis [4]
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Every package is shipped in temperature-stable packaging to protect peptide integrity during transit