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In this paradigm, aquaporin 8 silencing, which is specifically expressed in IMM, enhances mitochondrial ROS generation and results in mitochondrial depolarization and cell death ( 2 O 2 at higher rates than complex I from mitochondria (Quinlan et al., 2014)
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Norton, M
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Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+
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