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But again, retatrutide targets GLP-1 receptors as well as GIP receptors The GIP hormone works extremely similarly to GLP-1

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Related GI injuries that qualify include ileus (impaired bowel function where the intestines stop moving food through), intestinal obstruction, and severe gallbladder complications including the need for gallbladder removal after tirzepatide use

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Emerging evidence suggests that GIPR co-activation may mitigate the GI adverse effects commonly observed with GLP-1 RAs

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