Neurological symptoms may start improving within 12 weeks, but longstanding complications can require 36 months of treatment, with some damage potentially irreversible
Studies treating mild to moderate B12 deficiency in older people have failed to provide cognitive benefits: A clinical trial from the Netherlands measured the cognitive response to B12 supplements in people 70 years old with mild B12 deficiency and MMA levels 320 nmol/l (average: ~450 nmol/l)
Keep unused aliquots labeled with date, solvent, and concentration for later repeats
Most users tolerate 5-Amino-1MQ well, especially when prescribed and monitored by a qualified provider
Many local guidelines on B12 replacement therapy are also available
Vitamin B12 is an essential water-soluble vitamin that is crucial for the production of DNA, red blood cells, nerve cells and more