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Peer review Peer review information Nature Communications thanks Mitsuyasu Hasebe, Hiroaki Mano, Andrej Pavlovic and Michael Wudick for their contribution to the peer review of this work

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It has shown efficacy in animal models of inflammatory bowel disease (IBD), gastric ulcers, and "leaky gut." Systemic anti-inflammatory effects: It appears to dampen inflammatory cascades without the immune-suppressing risks associated with corticosteroids

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