The cardiorenal effects of both GLP-1RA and SGLT-2 inhibitors can be summarized as follows: GLP-1RA have moderate benefits on MACE (major cardiovascular events), may reduce all-cause mortality and hospitalization for HF (HHF), and have a robust effect in reducing the incidence of macroalbuminuria [12]
Yet to be explored disease areas that may soon attract interest include alcohol use disorder, other addictive disorders, and even oncology
Thus, timing matters avoid initiating during active wound repair phase
As more oral agents enter clinical practice, they may improve accessibility, adherence, and flexibility for patients, making individualized obesity care more achievable in real-world settings
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