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Since the original papers were published, the management of type 1 diabetes has advanced: continuous and flash glucose monitoring give us a much better idea of glucose variability within an individual, and we now regularly measure C-peptide levels and are starting to get a clearer view of residual beta-cell function in people with type 1 diabetes

They tracked the onset of dementia in subjects with type 2 diabetes who were being treated for their diabetes with either GLP-1 receptor agonists or metformin (87,229 subjects in each group with an average age of 58)

But stress, toxins, poor diet and other lifestyle factors that increase its use will speed up depletion

Effect of astaxanthin-rich extract derived from Paracoccus carotinifaciens on cognitive function in middle-aged and older individuals

120 key targets were screened out from the differentially expressed genes through RNA-Seq

J Clin Endocrinol Metab 91(1):4853