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For sterile injections, USP standards typically limit beyond-use dates to 10 days or less when refrigerated (for Category 2 compounding) unless extended through validated testing

Do not freeze it, and avoid leaving it at room temperature for extended periods

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A consistent deficit of around 500600 kcal per day broadly in line with NICE guidance would therefore be expected to yield approximately 0.450.5 kg per week (roughly 1 lb per week) during this phase

May relate to blood pressure effects in sensitive individuals