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Cemiplimab suggested a non-significant trend toward lower risk in older patients, while tremelimumab exhibited a large but imprecise effect estimate due to limited data

Ten trials 13,14,2632 had sufficient data for the meta-analysis (n=366 treatment, n=359 control), and five trials 15,26,3335 were excluded from quantitative synthesis due to incomplete or non-extractable data

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The 2-hour food buffer matters because insulin and growth hormone work against each other at the receptor level