Trial averages do not determine the best treatment for every individual
Your professional will monitor your progress and make any necessary adjustments to support your weight loss goals
Conditions such as Crohns, coeliac disease or previous gut surgery, and the autoimmune cause behind pernicious anaemia, all affect how well you retain B12
In addition to the improvement in HbA1c and glucose profile, tirzepatide has also demonstrated to improve insulin resistance, as assessed by HOMA-IR
Survodutide is a concrete bet on that principle, and the reason it is studied so intensively is that the bet is testable: if the glucagon axis truly adds something, it should show up as extra weight loss, extra liver-fat reduction, and a distinct safety signature relative to GLP-1 alone
The discordance between two reviewers was resolved through discussion with another reviewer (ZW) until all the researchers reached a consensus