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So, if your vitamin B12 is not working properly because your folate metabolism isnt working properly this causes homocysteine imbalances which are considered a serious health problem for anyone especially for those with MTHFR gene mutations. 4 Reactions to Methylfolate supplementation Individuals that cannot tolerate Methylfolate often have low B12 levels in their cells
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Whilst semaglutide does not typically cause cognitive impairment, patients taking both medications should be monitored for any changes in mental function, particularly if topiramate doses are increased
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Other drugs may be available that can treat your condition