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Gs-protein activation also increases heart rate (chronotropy) by increasing phase 4 pacemaker currents in the sinoatrial node

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EF: Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

Delton Family Distinguished Professor in Organic Chemistry, and Joshua Munger, professor in the Department of Biochemistry and Biophysics and an expert in cancer cell metabolismare exploring ways to refine potential drugs that could inhibit this process and improve outcomes for patients

The FDA approves them based on a series of clinical trials that prove efficacy and most importantly safety