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Collectively, these recent contributions argue that future GSH-centric redox sensing and nanomedical approaches should (i) incorporate organelle targeting (especially mitochondria) to exploit subcellular redox heterogeneity, (ii) embed analyte-responsive activation into both therapeutic and imaging components, (iii) combine biochemical sensing with optical or thermal engineering for spatiotemporal control, and (iv) favor clinically translatable carriers (e.g., PLGA) for delivery

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CrossRef Dihydroartemisinin inhibits histone lactylation through YAP1 to act as a hot switch for cold tumor in hepatocellular carcinoma Yuting Gao, Yi Gong, Xiaoyong Song, Yajun Xiong, Junlan Lu, Yanguang Yang, Yanli Gong, Zhimin Du, Shanshan Wang, Ruilong Jia, Peng Gong, Xinli Shi Phytomedicine .2025

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For male infertility: 1 gram of acetyl-L-carnitine plus 2 grams of L-carnitine has been taken daily to treat male infertility For male infertility secondary to abacterial prostatovesiculoepididymitis: 500 mg of acetyl-L-carnitine plus 1 gram of L-carnitine every 12 hours has been used following 2 months of treatment with nonsteroidal anti-inflammatory drugs (NSAIDs)