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In the known GS, the AA-motif is conserved, whereas, the LP-motif is found in the known hGS from various legumes

28,36 Theoretically, the substitution of Gly 22 with Ala would make the -helix more stable, but increments in the affinity and activity were not found

Johannes, Buse JB, Idorn T, et al

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Emotional distress is a common risk in women with polycystic ovary syndrome: a systematic review and meta-analysis of 28 studies