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Anemia and PMS may both cause symptoms headache tiredness and fatigue depression cravings and changes in appetite Heavy periods Signs that heavy periods might be causing anemia A heavy period means needing to change a tampon or pad within If heavy periods are causing anemia, people may experience: fatigue weakness shortness of breath paleness feeling dizzy or faint headache reduced concentration Treating the cause of heavy periods and restoring iron levels may help treat anemia