TRT has direct metabolic effects, including: Muscle growth : Testosterone directly stimulates muscle protein synthesis, growth, and repair, especially of the fast-twitch muscle fibers that power strength and hypertrophy, says Lee
He adds that regularly missing doses can increase side effects and reduce the overall effectiveness of the medication, leading to slower weight loss or potentially weight gain
Semaglutide is recommended for adults seeking medically supervised weight management with structured dosing, ongoing monitoring, and evidence-based outcomes.
Medical Considerations and Who Should Expect Slower or Faster Early Response Patients with type 2 diabetes may see faster initial weight loss due to improved glucose control reducing hunger signals
Ophthalmology 111 , 16411648 (2004)
2022 Mar 7;79(6):512-513]